Preliminary Evaluation of the Interactions of Panax ginseng and Salvia miltiorrhiza Bunge with 5-Fluorouracil on Pharmacokinetics in Rats and Pharmacodynamics …

C Gu, J Qiao, M Zhu, J Du, W Shang, W Yin… - The American Journal …, 2013 - World Scientific
… It is therefore important to study the potential consequences of the interactions … from Panax
ginseng (PGS) and Salvia miltiorrhiza Bunge (SMB) on the pharmacokinetics of 5-fluorouracil (…

[HTML][HTML] A review of the pharmacodynamic effect of chemo-herbal drug combinations therapy for cancer treatment

A Okem, C Henstra, M Lambert, R Hayeshi - Medicine in Drug Discovery, 2022 - Elsevier
Salvia miltiorrhiza Bunge Oxaliplatin glioblastoma Relieve … growth of tumours and prolong
the survival time of mice. H22 … The Ginseng species, Panax ginseng and 5-fluorouracil both …

Simultaneous determination of the novel anti-tumor candidate drug MDH-7 and 5-fluorouracil in rat plasma by LC-MS/MS: Application to pharmacokinetic interactions

J Li, Y Chen, P Zhou, Q Fan, Q Wang, X Chen… - … of Chromatography B, 2018 - Elsevier
Preliminary pharmacokinetic studies showed that MDH-7 had a wide range of … interactions
may be mediated by physicochemical properties, pharmacokinetic and pharmacodynamic

Panax ginseng and Salvia miltiorrhiza supplementation during eccentric resistance training in middle-aged and older adults: A double-blind randomized control trial

HF Lin, CC Chou, HH Chao, H Tanaka - Complementary therapies in …, 2016 - Elsevier
… envelope and revealed after all the preliminary data analysis was performed. During the
study… , more studies are needed to address cellular mechanisms associated with this interaction. …

A comprehensive review of recent studies on herb-drug interaction: a focus on pharmacodynamic interaction

JG Choi, SM Eom, J Kim, SH Kim, E Huh… - The Journal of …, 2016 - liebertpub.com
… by examining pharmacodynamic (PD) and pharmacokinetic (… as using experimental animals,
such as mice, rats, or dogs. In … of 5-fluorouracil in HCT116 human colon cancer cell line 47 …

Herbal Medicines as Adjuncts to Cancer Chemotherapy—Part 1: Immunomodulators

E Yarnell, C Zimmerman - Alternative and Complementary …, 2019 - liebertpub.com
Preliminary evaluation of the interactions of Panax ginseng and Salvia miltiorrhiza Bunge
with 5-fluorouracil on pharmacokinetics in rats and pharmacodynamics in human

Ginsenoside Rh2 induces apoptosis and inhibits epithelial-mesenchymal transition in HEC1A and Ishikawa endometrial cancer cells

JH Kim, M Kim, SM Yun, S Lee, JH No, DH Suh… - Biomedicine & …, 2017 - Elsevier
… On the other hand, Rh2, a well-characterized component in red ginseng, has been shown
to inhibit the growth of many types of human cancer cells by inducing cell cycle arrest and …

[HTML][HTML] American ginseng significantly reduced the progression of high-fat-diet-enhanced colon carcinogenesis in ApcMin/+ mice

C Yu, XD Wen, Z Zhang, CF Zhang, X Wu, X He… - Journal of Ginseng …, 2015 - Elsevier
Preliminary evaluation of the interactions of Panax ginseng and Salvia miltiorrhiza Bunge
with 5-fluorouracil on pharmacokinetics in rats and pharmacodynamics in human

Impact of Drug Metabolism/Pharmacokinetics and their Relevance Upon Salviabased Drug Discovery

DC Hao, PG Xiao - Current Drug Metabolism, 2017 - ingentaconnect.com
… of various Salvia species, especially Salvia miltiorrhiza, are … impact the PK/pharmacodynamic
performance of compounds … Salvia miltiorrhiza gradients in rat plasma and brain by LC- …

[PDF][PDF] Medicine in Drug Discovery

A Okem, C Henstra, M Lambert, R Hayeshi - researchgate.net
… The Ginseng species, Panax ginseng and 5fluorouracil both show an … Preliminary Evaluation
of the Interactions of Panax ginseng and Salvia miltiorrhiza Bunge with 5-Fluorouracil on …